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Condition guide
Erectile dysfunction —
causes & treatment
1 in 3
95%
Respond to PDE5 treatment
30M+
US men with ED
80%
Men over 40 affected
ED medicines
From $80
From $80
From $88
From $95
From $70
What is erectile dysfunction?
Erectile dysfunction (ED) is the inability to achieve or maintain an erection firm enough for satisfactory sexual intercourse. It affects an estimated 30 million men in the United States alone — and yet remains one of the most undertreated conditions in men’s health, largely due to embarrassment.
ED is not a life sentence. In the vast majority of cases it is entirely treatable. PDE5 inhibitors like sildenafil (the active ingredient in Cenforce and Viagra®) are effective in over 90% of men with ED, often producing noticeable improvement from the first dose.
Common causes of ED
ED has physical causes in about 80% of cases, psychological causes in roughly 10%, and a combination of both in the remaining 10%.
Physical causes
- Cardiovascular disease
- Diabetes (type 1 & 2)
- High blood pressure
- Low testosterone
- Obesity
- Medication side effects
- Nerve damage
Psychological causes
- Performance anxiety
- Depression
- Chronic stress
- Relationship difficulties
- Low self-confidence
- Past trauma
Treatment options
Sildenafil (Cenforce)
Most prescribed first-line treatment. Works in 30–60 min. Effective in 90%+ of cases. From $80.
Tadalafil (generic Cialis)
Longer-acting alternative. Lasts up to 36 hours. Available as a daily dose option.
Lifestyle changes
Exercise, weight loss, stopping smoking and reducing alcohol can significantly improve ED.
Psychological support
For psychologically-driven ED, therapy is often more effective than medication alone.
Dr. James Mitchell, PharmD, MBA
Lead Pharmacist · Reviewed May 2025
ED is almost always treatable. Sildenafil is where I'd start for most men — it's the most studied oral ED drug in the world, extremely affordable in generic form, and works for the vast majority of patients. Don't wait years to address this. It's one of the most responsive conditions in men's health to appropriate treatment.