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Sildenafil typically lasts 4–6 hours, though individual response varies considerably. Here’s everything you need to know about timing, duration, and how to get the best results.
| Dose | Typical duration | Notes |
|---|---|---|
| 25mg | 3–4 hours | Shorter duration, suitable for sensitive patients |
| 50mg | 4–5 hours | Common starting dose |
| 100mg | 4–6 hours | Standard dose, most men |
| 150mg | 5–7 hours | Longer potential duration |
| 200mg | 6–8 hours | Maximum dose — not recommended as first choice |
Several factors influence duration:
• Food: A high-fat meal before taking sildenafil delays absorption and can reduce peak concentration, shortening effective duration.
• Age: Older men may experience longer duration as drug clearance slows with age.
• Alcohol: Moderate alcohol doesn’t significantly affect duration, but heavy drinking reduces effectiveness overall.
• Metabolism: Individual metabolic rate affects how quickly sildenafil is processed.
Take sildenafil 30–60 minutes before planned sexual activity. For fastest onset, take it on an empty stomach or after a light, low-fat meal. The drug is active for 4–6 hours — sexual stimulation is required for it to work during this window.
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Lead Pharmacist · Reviewed May 2025
This article is reviewed by a licensed pharmacist and updated regularly. For personalised medical advice, please consult your own healthcare provider before starting any new medication.